Ddp ic50
WebIC50 of DDP and the expression level of miR-1236-3p in A549 and A549/DDP cells. (A) The concentration of 20 μg/ml-DDP was added to verify the IC50 values in A549 and … WebAmphenol ICC (FCI) Manufacturer Product Number. DDM50P. Description. CONN D-SUB PLUG 50P SLDR CUP. Manufacturer Standard Lead Time. 11 Weeks. Detailed …
Ddp ic50
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WebJun 8, 2024 · The IC 50 of OVCAR3/DDP and OVCAR3 cells were 122.30±2.83 and 66.08±5.25, respectively, and the index (RI) of OVCAR3/DDP cells was 1.87 ( Fig. 1C ). These results indicated that OVCAR3/DDP cells had increased resistance to cisplatin compared with OVCAR3 cells. Figure 1. Establishment of the cisplatin-resistant cell line … WebAug 13, 2010 · Curcumin could significantly inhibit A549 and A549/DDP cells growth in MTT assays, and the inhibition ratio was markedly increased in a dose- and time-dependent manner (Fig. 1A).The IC50 of curcumin at 48 h were 16.28 ± 1.4 μmol/L for A549 cells and 18.06 ± 1.9 μmol/L for A549/DDP cells (Fig. 1B), which were not significantly different (P …
WebIn A549/DDP cells, GAS5 showed the similar effect as 3-MA in reducing DPP IC50 and promoting DDP-induced apoptosis and also presented synergic effect with 3-MA. CONCLUSIONS: GAS5 downregulation is associated with cisplatin resistance in NSCLC. GAS5 can inhibit autophagy and therefore enhance cisplatin sensitivity in NSCLC cells. … WebThe 50 % inhibitory concentration (IC50) of cisplatin in A549 and A549/DDP cells 48 h after drug treatment Source publication +4 RNA interferences targeting the Fanconi …
WebNov 9, 2024 · The IC50 of NSCLC cells to DDP was measured by CCK-8 assay. NSCLC cell proliferation and apoptosis were observed by clone formation assay and flow cytometry. The content of m6A in total RNA in tissues and cells of NSCLC patients was detected using m6A Methylation Quantification Kit. The expressions of DGCR8-bound pri-miR-19a and m6A … WebGemcitabine (LY-188011, NSC 613327) HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, …
WebMar 22, 2024 · The drug’s IC 50 values indicated that the cells had acquired a stable CDDP-resistance phenotype, with the IC 50 values of the A549/DDP cells remaining …
WebTerms and conditions. IC50 of DDP and the expression level of miR-1236-3p in A549 and A549/DDP cells. (A) The concentration of 20 μg/ml-DDP was added to verify the IC50 values in A549 and A549 ... porvoon kaupunki sivistystoimiWebDDP with IC50 of 57.7 and 86.2 μM was obtained for A549 cells with empty vector or USP14 expression vector transduction, respectively (Figure 2B). Moreover, apoptosis rates were higher in A549/DDP cells with relatively low USP14 expression compared with the rates in control cells (siNC) (Figure 2C,E ). porvoon kaupunki palauteWebNov 13, 2024 · The DDP IC50 values for DDP‑resistant MGC803/DDP cells were greater than those for MGC803 cells. Furthermore, MGC803/DDP cells exhibited increased levels of viability, migration and invasion, and decreased levels of apoptosis and DNA damage during DDP treatment. Knockdown of RAP2A expression significantly promoted MGC803/DDP … porvoon kaupunki koulutWebThe chemosensitivities of EOC cells to DDP were tested and half maximal inhibitory concentration (IC50) was measured by methyl thiazolyl tetrazolium (MTT) and flow … porvoon kaupunki röntgenWebAug 27, 2024 · Meanwhile, the IC50 values of DDP and sodium butyrate in the HGC-27 cells at 24 h were about 4 µg/ml and 10 mM. Then, the HGC-27 and SGC-7901 cells were exposed to combinations of cisplatin and … porvoon kaupunki matala kynnysporvoon kaupunki suun terveydenhuoltoWebOct 1, 2024 · The DDP at a concentration of IC50 (AGS/DDP cells, 71.34 μM; MKN45/DDP cells, 61.28 μM) was used for further experiments. Bax and Bcl-2 are biomarkers of apoptosis. As illustrated in Figure 2E , the protein expression of Bax was remarkably elevated, while Bcl-2 was declined in AGS/DDP and MKN45/DDP cells following sh … porvoon kaupunki organisaatio