Phospho dap12 antibody
WebJun 21, 2024 · DAP12 consists of a minimal extracellular domain, a transmembrane segment and a cytoplasmic region containing a single immunoreceptor tyrosine-based … WebMay 18, 2010 · The ITAM of DAP12 (SPY 65 QELQGQRPEVY 76 SDL) contains two critical tyrosines, Tyr 65 and Tyr 76, which are needed to recruit the kinase Syk, which harbors …
Phospho dap12 antibody
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WebSanta Cruz Biotechnology, Inc. offers a broad range of DAP12 antibodies. Select DAP12 antibodies from monoclonal antibodies listed below. View detailed DAP12 antibody specifications by linking to the specific product blocks. Select appropriate DAP12 antibodies for your research by isotype, epitope, applications and species reactivity. To the ... WebDAP12, also known as TYROBP and KARAP, is a transmembrane protein that functions as a signal transduction adaptor molecule. DAP12 is expressed as a disulfide-linked homodimer that associates with a variety of receptors on NK and myeloid cells. Complex formation is mediated by intramembrane ionic interaction between an aspartic acid residue in ...
WebSynthetic peptide corresponding to Human DAP12 aa 50 to the C-terminus conjugated to keyhole limpet haemocyanin. (Peptide available as ab107906) Positive control This antibody gave a positive signal in the follwoing lysates: Lung (Human) Tissue Lysate. General notes WebAug 14, 2024 · AL002a promoted TREM2-dependent DAP12 and Syk phosphorylation. Panel a shows that AL002a binds to BMM derived from WT, but not Trem2 KO mice, as measured by FACS. A rat anti-Trem2 antibody from R&D Systems was used as a positive binding control and an isotype msIgG1 antibody as a negative control.
WebRabbit polyclonal antibody raised against synthetic phosphopeptide of ABL1/ABL2. Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y393/Y429 of human ABL1/ABL2. (PAB12190) - Products - Abnova WebPhospho-PAK1 (Thr84) Classification: Polyclonal: Formule: 0.1M HEPES with 0.15M NaCl, 0.1mg/mL BSA, 50% glycerol and no preservative; pH 7.5: Numéro d’ordre du gène: Q13153, O88643: Symboles de gène(s) PAK1: Immunogène: Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr84 of human PAK1 conjugated to …
WebJun 21, 2024 · Ligation of a DAP12-associated receptor to its ligand leads to the activation of SRC-family kinases and subsequent phosphorylation of tyrosine residues in the ITAM of DAP12 ( Mason et al., 2006 ). DAP12 was originally shown to trigger the activation of NK cells ( Lanier et al., 1998 ).
WebHowever, detection of phosphorylated proteins in western blots can be challenging. At Bio-Rad, we have developed 10 tips to ensure robust data generation and cleaner blots. Topics include: Inhibition of protein degradation and conservation of post-translational modifications during sample preparation. Selection of phospho-specific antibodies. cuddlist kansas cityWebMonoclonal Antibody for studying Bad (Ser99) phosphate. Cited in 1 publication. Highly specific and rigorously validated in-house, Phospho-Bad (Ser136) (5D8) Mouse Monoclonal Antibody (CST #5282) is ready to ship. ... Phospho-Bad (Ser136) (5D8) Mouse mAb can be used in high throughput kinase assays and drug discovery applications. It detects ... easter in pamplonaWebApr 6, 2024 · 在缺氧mdcs 上，trem-1 与dap12 有关，其啮合引起dap12 相连的信号，造成erk 1 、akt ，鼻息肉组织磷 酸化和炎性细胞因子的趋化因子的分泌。 最后，我们提供了第一个 ，TREM-1 在mDCs 上的表达会造成儿童的特发性关节炎，作为一个在体内具 有促炎性的缺氧mDCs 上的新 ... cuddling with best friendWebAll lanes : Anti-DAP12 antibody [EPR24244-76] (ab283679) at 1/1000 dilution Lane 1 : RAW264.7 (mouse Abelson murine leukemia virus-induced tumor macrophage), whole … cuddling with guinea pigsWebJun 18, 2024 · Microglia plays crucial roles in Alzheimer’s disease (AD) development. Triggering receptor expressed on myeloid cells 2 (TREM2) in association with DAP12 mediates signaling affecting microglia function. Here we study the negative regulation of TREM2 functions by leukocyte immunoglobulin-like receptor subfamily B member 2 … cuddling with someone you\u0027re not datingWebPhosphospecific antibodies are affinity-purified rabbit polyclonal or monoclonal antibodies that are monospecific for a target protein that is phosphorylated. These antibodies … easter in other languagesWebYour search returned 77 DAP12 Flow Cytometry Antibodies across 10 suppliers. Showing 10 of 10 suppliers (77 products total) > >> Select All. Select up to 5 products from below to compare or request more information. Request Info for … cuddling with your boyfriend couch