WebProduct Details Target Information The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. WebRecombinant Recombinant Anti-eIF4B (phospho S406) antibody [EPR7683] (ab134138) Datasheet SDS Submit a review Submit a question References (2) Key features and details Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal [EPR7683] to eIF4B (phospho S406) Suitable for: …
Loss of SLC25A11 causes suppression of NSCLC and melanoma …
WebPhospho-EIF4B (Ser406) EIF4B (Eukaryotic Translation Initiation Factor 4B) is a Protein Coding gene. Among its related pathways are Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include nucleic acid binding ... WebPhospho-EIF4B-S422 Rabbit pAb (AP0775) Datasheet SDS Tested applications: WB Reactivity: Human Western blot analysis of extracts of HeLa cells, using Phospho-EIF4B-S422 antibody (AP0775) at 1:2000 dilution. HeLa cells were treated by EGF (100ng/mL) for 30 minutes after serum-starvation overnight. northampton bank
Phospho-eIF4B (Ser406) Polyclonal Antibody (28779-1-AP)
WebeIF4B (eukaryotic translation initiation factor 4B), an RNA binding protein, is essential for the binding of mRNA to the 43S pre-initiation complex, which consists of the 40S ribosomal … WebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins are EIF4A, EIF4F. eIF4B is involved in translation of numerous proliferative or anti-apoptotic mRNAs with highly structured 5'UTR and subsequently affect cell growth … WebAug 17, 2014 · Phospho-proteomics identified the mTOR pathway to be of interest in EGFR inhibitor resistance. In our studies, combining gefitinib and temsirolimus decreased cell growth and survival in a synergistic manner. Our data identified eIF4B, as a potentially key fragile point in EGFR and mTOR inhibitor synergy. how to repair lol client 2023