WebIn pharmacology, clearance is a pharmacokinetic measurement of the volume of plasma from which a substance is completely removed per unit time. Usually, clearance is … WebBiological half-life (also known as elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (C max) to half of C max in the blood plasma, and is denoted by the abbreviation .. This is used to measure the removal of things such as metabolites, …

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WebOct 1, 2004 · The pharmacokinetics of the new generation of inhalational anaesthetics are affected only slightly by obesity. Ideal body weight is useful when assessing dosage of many (but not all) modern anaesthetic drugs. Recent target-controlled infusion (TCI) models for propofol, remifentanil and sufentanil consider age, gender, weight and height as ... Webwhere CL T is the total clearance, CL H is the hepatic clearance, CL R is the renal clearance, and CL other represents the sum of all other clearance processes.. ♦. The total clearance is considered the most useful pharmacokinetic parameter because it is a direct indicator of organ function and can be used to predict the average concentration or steady-state … free coffee at starbucks

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Web“Part of the total clearance due to liver enzyme activity and biliary excretion” Description. Hepatic clearance quantifies the loss of drug during its passage through the liver. Hepatic … WebThe following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of … Webtotal clearance: 1. The sum of the clearances from each organ or tissue participating in the elimination of a substance from the body. 2. The volume or mass of tissue cleared of a … free coffee at wawa today